产品货号:
Z16726
中文名称:
GPBAR1抗体
英文名称:
Anti-GPBAR1 Antibody
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-GPBAR1 Antibody |
指标别名 | GPBAR1;TGR5;G-protein coupled bile acid receptor 1;G-protein coupled receptor GPCR19;hGPCR19;Membrane-type receptor for bile acids;M-BAR;hBG37;BG37 |
克隆性 | Polyclonal |
检验物种 | mouse,rat |
应用范围 | WB |
基因名称 | GPBAR1 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | A synthetic peptide corresponding to a sequence of human GPCR TGR5/GPBAR1 (DQRYTAPWRAAAQR). |
实际分子量 | 45KD |
成分 | 500μg/mL antibody with PBS,0.02% NaN3,1mg BSA and 50% glycerol. |
纯化方式 | Immunogen affinity purified. |
浓度 | 500μg/mL |
产品形态 | 溶液 |
保存条件 | 12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
背景资料 | The G protein-coupled bile acid receptor 1 (GPBAR1) also known G-protein coupled receptor 19 (GPCR19),membrane-type receptor for bile acids (M-BAR) or TGR5 as is a protein that in humans is encoded by the GPBAR1 gene.This gene encodes a member of the G protein-coupled receptor (GPCR) superfamily.This enzyme functions as a cell surface receptor for bile acids.Treatment of cells expressing this GPCR with bile acids induces the production of intracellular cAMP,activation of a MAP kinase signaling pathway,and internalization of the receptor.The receptor is implicated in the suppression of macrophage functions and regulation of energy homeostasis by bile acids.Alternative splicing results in multiple transcript variants encoding the same protein. |
Uniprot ID | Q8TDU6 |
推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot. |
基因名全称 | G protein-coupled bile acid receptor 1 |
蛋白名全称 | G-protein coupled bile acid receptor 1 |
推荐稀释比 | Western blot(WB) 1:500~2000 |
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